Local therapy must be tailored to each patient’s needs.

Here a list of some active substances for topical treatment:

• calcipotriol, a synthetic substance identical to vitamin D used for treating plaque psoriasis. The product is applied twice a day (after skin cleansing) to a quantity that does not exceed 100 grams a week(100 gr. is the equivalent of 3 packs of the drug)

• calcitriol is a naturally occurring active form of Vitamin D3. It has a lesser itchy effect compared to other similar substances. It should be applied to the skin affected by the lesions tiwice a day,after skin cleansing.
  N.B. Vitamin D drugs or their derivatives are not meant to be used for pustular and erythrodermic psoriasis because it can increase the risk of getting hypercalcemia, a condition in which the calcium level in your blood is above normal, that can occur in both acute and chronic forms

• tazarotene a vitamin A derivative, is an effective treatment for plaque psoriasis. It can cause a mild irritation(itch and eryhtema) as a side effect and so it is strongly advised applying the product only on psoriasis plaques

• steroid drugs, such as betamethasone, are used for the treatment of numerous inflammatory diseases (bronchial asthma, rheumatoid arthritis, severe allergies) and in some neoplasms,esepcially for the lymphatic tissue. Topical medications (cream, medicated patches) are used for the treatment of inflammatory events and skin allergies; in psoriasis topical steroids are often used in combination with vitamin D derivatives

Alongside the pharmacological treatment, an adequate adjuvant, exfoliating, moisturizing and soothing treatment contributes to the restoration of skin functions.